|
Course Discription |
:
This practical course in medicinal chemistry concerned with multistep synthesis of selected medicinal compounds. The successful medicinal chemist is an expert organic chemist who has, or can acquire, sufficient knowledge in other disciplines to apply that knowledge to drug synthesis and design. We shall have opportunities to illustrate the dependence of medicinal chemistry on knowledge from other disciplines as we progress through this course. So our course will build on the experience gained from organic chemistry lab through the synthesis and characterization of complex molecules, the acquisition and interpretation of physical data and the investigation of chemical systems through computational techniques gained in analytical and instrumental labs. It consists of a series of laboratory-based experiments aimed at developing skills in the synthesis, safe handling and analysis of chemical substances of a range of different classes of compounds; an understanding of modern characterization techniques (e.g. chromatography, atomic and molecular spectroscopy), and the operation of instrumentation for the acquisition of kinetic, structural and thermodynamic data. |